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Results for ANK3


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ANK3

Description
ankyrin 3
Aliases
ANKYRIN-G, MRT37

Gene Identifiers

Entrez ID
288
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001149.3; NM_001204403.2; NM_001204404.2; NM_001320874.2; NM_020987.5; XM_005269715.3; XM_006717796.3; XM_006717802.3; XM_011539708.2; XM_011539709.2; XM_017016110.1; XM_017016111.1; XM_017016112.1; XM_017016113.1; XM_017016114.1; XM_017016115.1; XM_017016116.1; XM_017016117.1; XM_017016118.1; XM_017016119.1; XM_017016120.1; XM_017016121.1; XM_017016122.1; XM_017016123.1; XM_017016124.1; XM_017016125.1; XM_017016126.1; XM_017016127.1; XM_017016128.1; XM_017016129.1; XM_017016130.1; XM_017016131.1; XM_017016132.1; XM_017016134.1; XM_017016136.1; XM_017016137.1; XM_017016138.1; XM_017016141.1; XM_024447953.1; XM_024447954.1; XM_024447955.1; XM_024447956.1; XM_024447957.1; XM_024447958.1; XM_024447959.1; XM_024447960.1; XM_024447961.1; XM_024447962.1; XM_024447963.1; XM_024447964.1; XM_024447965.1

Protein Identifiers

RefSeq (protein)
NP_001140.2; NP_001191332.1; NP_001191333.1; NP_001307803.1; NP_066267.2; XP_005269772.1; XP_006717859.1; XP_006717865.1; XP_011538010.1; XP_011538011.1; XP_016871599.1; XP_016871600.1; XP_016871601.1; XP_016871602.1; XP_016871603.1; XP_016871604.1; XP_016871605.1; XP_016871606.1; XP_016871607.1; XP_016871608.1; XP_016871609.1; XP_016871610.1; XP_016871611.1; XP_016871612.1; XP_016871613.1; XP_016871614.1; XP_016871615.1; XP_016871616.1; XP_016871617.1; XP_016871618.1; XP_016871619.1; XP_016871620.1; XP_016871621.1; XP_016871623.1; XP_016871625.1; XP_016871626.1; XP_016871627.1; XP_016871630.1; XP_024303721.1; XP_024303722.1; XP_024303723.1; XP_024303724.1; XP_024303725.1; XP_024303726.1; XP_024303727.1; XP_024303728.1; XP_024303729.1; XP_024303730.1; XP_024303731.1; XP_024303732.1; XP_024303733.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
600465
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 262/7921 TCGA samples
  • Damaged in 59/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 75 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 8 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1122 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 2 cell lines
  • Response/resistance in 0 trials