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Results for ARNTL


Expand for information on ARNTL

ARNTL

Description
aryl hydrocarbon receptor nuclear translocator like
Aliases
BMAL1, BMAL1c, JAP3, MOP3, PASD3, TIC, bHLHe5

Gene Identifiers

Entrez ID
Ensembl Gene ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Candidate cancer driver
  • Damaged in 55/7921 TCGA samples
  • Damaged in 15/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 95 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 33 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1121 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials