Home Query results

Results for ASCC2


Expand for information on ASCC2

ASCC2

Description
activating signal cointegrator 1 complex subunit 2
Aliases
ASC1p100, p100

Gene Identifiers

Entrez ID
84164
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001242906.2; NM_001369920.1; NM_001369921.1; NM_001369922.1; NM_001369923.1; NM_001369924.1; NM_001369925.1; NM_001369926.1; NM_001369927.1; NM_001369928.1; NM_001369929.1; NM_001369930.1; NM_001369931.1; NM_001369932.1; NM_001369933.1; NM_001369934.1; NM_001369935.1; NM_001369936.1; NM_001369937.1; NM_001369938.1; NM_001369939.1; NM_001369940.1; NM_001369941.1; NM_001369942.1; NM_001369943.1; NM_001369944.1; NM_001369945.1; NM_001369946.1; NM_001369947.1; NM_001369948.1; NM_001369949.1; NM_001369950.1; NM_032204.5; XM_011530442.3; XM_011530443.2; XM_011530444.2; XM_011530445.2; XM_011530448.2; XM_011530450.2; XM_011530451.2; XM_011530452.2; XM_011530453.2; XM_011530454.2; XM_011530455.2; XM_017028992.1; XM_017028996.1; XM_017028998.1; XM_017029005.1; XM_024452287.1; XM_024452288.1; XM_024452289.1; XM_024452290.1; XM_024452291.1; XM_024452292.1

Protein Identifiers

RefSeq (protein)
NP_001229835.1; NP_001356849.1; NP_001356850.1; NP_001356851.1; NP_001356852.1; NP_001356853.1; NP_001356854.1; NP_001356855.1; NP_001356856.1; NP_001356857.1; NP_001356858.1; NP_001356859.1; NP_001356860.1; NP_001356861.1; NP_001356862.1; NP_001356863.1; NP_001356864.1; NP_001356865.1; NP_001356866.1; NP_001356867.1; NP_001356868.1; NP_001356869.1; NP_001356870.1; NP_001356871.1; NP_001356872.1; NP_001356873.1; NP_001356874.1; NP_001356875.1; NP_001356876.1; NP_001356877.1; NP_001356878.1; NP_001356879.1; NP_115580.2; XP_011528744.1; XP_011528745.1; XP_011528746.1; XP_011528747.1; XP_011528750.1; XP_011528752.1; XP_011528753.1; XP_011528754.1; XP_011528755.1; XP_011528756.1; XP_011528757.1; XP_016884481.1; XP_016884485.1; XP_016884487.1; XP_016884494.1; XP_024308055.1; XP_024308056.1; XP_024308057.1; XP_024308058.1; XP_024308059.1; XP_024308060.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
614216
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 94/7921 TCGA samples
  • Damaged in 11/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 86 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 4 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 3/1064 cell lines

Gene Function

  • Not present in KEGG
  • 1/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials