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Results for ATAD3B


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ATAD3B

Description
ATPase family AAA domain containing 3B
Aliases
AAA-TOB3, TOB3

Gene Identifiers

Entrez ID
83858
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
612317
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 39/7921 TCGA samples
  • Damaged in 13/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • One duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 87 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with one miRNA

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 10/1093 cell lines

Gene Function

  • Not present in KEGG
  • 1/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials