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Results for ATP5PD


Expand for information on ATP5PD

ATP5PD

Description
ATP synthase peripheral stalk subunit d
Aliases
APT5H, ATP5H, ATPQ

Gene Identifiers

Entrez ID
10476
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
618121
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 106/7921 TCGA samples
  • Damaged in 4/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • 4 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 124 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with one miRNA

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 40/1029 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials