Home Query results

Results for BUD23


Expand for information on BUD23

BUD23

Description
BUD23 rRNA methyltransferase and ribosome maturation factor
Aliases
HASJ4442, HUSSY-3, MERM1, PP3381, WBMT, WBSCR22

Gene Identifiers

Entrez ID
114049
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
615733
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 121/7921 TCGA samples
  • Damaged in 7/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 25 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 15 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 903/1015 cell lines

Gene Function

  • Not present in KEGG
  • 1/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials