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CAMKK2
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CAMKK2
Description
calcium/calmodulin dependent protein kinase kinase 2
Aliases
CAMKK, CAMKKB
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001270485.2; NM_001270486.1; NM_006549.3; NM_153499.2; NM_153500.1; NM_172214.3; NM_172215.3; NM_172216.1; NM_172226.2; XM_005253822.3; XM_005253823.1; XM_005253824.3; XM_011537763.1; XM_011537764.2; XM_017018694.1; XM_017018695.1; XM_017018699.1; XM_017018700.1; XM_017018702.2; XM_017018703.1; XM_017018705.1; XM_017018706.1; XM_017018708.1; XM_017018709.2; XM_024448798.1; XM_024448799.1
Protein Identifiers
RefSeq (protein)
NP_001257414.1; NP_001257415.1; NP_006540.3; NP_705719.2; NP_705720.1; NP_757363.1; NP_757364.1; NP_757365.1; NP_757380.1; XP_005253879.1; XP_005253880.1; XP_005253881.1; XP_011536065.1; XP_011536066.1; XP_016874183.1; XP_016874184.1; XP_016874188.1; XP_016874189.1; XP_016874191.1; XP_016874192.1; XP_016874194.1; XP_016874195.1; XP_016874197.1; XP_016874198.1; XP_024304566.1; XP_024304567.1
Uniprot ID
A0A024RBQ0; Q96RR4; Q96RR4; Q96RR4; A0A024RBQ0; A0A024RBP6; Q96RR4; A0A024RBQ3; Q96RR4; Q96RR4; Q96RR4; A0A024RBP8; Q96RR4; Q96RR4; A0A024RBP6; A0A024RBP8; Q96RR4; Q96RR4; A0A024RBQ3; Q96RR4; Q96RR4
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 44/7921 TCGA samples
- Damaged in 13/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants