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Results for CD36

Expand for information on CD36

CD36

Description

CD36 molecule

Aliases

BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3

Gene Identifiers

Entrez ID

948

Ensembl Gene ID

ENSG00000135218

mRNA Identifiers

RefSeq (mRNA)

NM_000072.3; NM_001001547.3; NM_001001548.2; NM_001127443.1; NM_001127444.2; NM_001289908.1; NM_001289909.1; NM_001289911.2; NM_001371074.1; NM_001371075.1; NM_001371077.1; NM_001371078.1; NM_001371079.1; NM_001371080.1; NM_001371081.1; XM_005250715.5; XM_024447002.1; XM_024447003.1

Protein Identifiers

RefSeq (protein)

NP_000063.2; NP_001001547.1; NP_001001548.1; NP_001120915.1; NP_001120916.1; NP_001276837.1; NP_001276838.1; NP_001276840.1; NP_001358003.1; NP_001358004.1; NP_001358006.1; NP_001358007.1; NP_001358008.1; NP_001358009.1; NP_001358010.1; XP_005250772.1; XP_024302770.1; XP_024302771.1

Uniprot ID

P16671; A4D1B1; P16671; A4D1B1; P16671; A4D1B1; P16671; A4D1B1; P16671; A4D1B1; P16671; B7Z6C3; P16671; B7Z6C3; E9PLT1; B7Z6C3; P16671; A4D1B1; A4D1B1; P16671

Ensembl protein ID

ENSP00000378268.3; ENSP00000308165.7; ENSP00000415743.2; ENSP00000411411.1; ENSP00000392298.2; ENSP00000401863.2; ENSP00000439543.1; ENSP00000431296.1; ENSP00000399421.1; -

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

173510

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Candidate cancer driver
Damaged in 136/7921 TCGA samples
Damaged in 18/1291 cell lines

Evolutionary Conservation

Last Universal Common Ancestor

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

28/30 tissues in GTEx
43/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

142/1019 in CCLE
946/970 in CLP
83/675 in GenenTech

Protein Expression in Tissues

9/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 24 protein(s)
Part of at least one complex

miRNA Interactions

Interacts with 20 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Equal damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Not essential in 1120 cell lines

Gene Function

4/6 level 1 KEGG pathways
6/26 level 1 Reactome pathways

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers