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Results for CLASP2


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CLASP2

Description
cytoplasmic linker associated protein 2
Aliases

Gene Identifiers

Entrez ID
23122
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001207044.3; NM_001365627.1; NM_001365628.1; NM_001365629.1; NM_001365630.1; NM_001365631.1; NM_001365632.1; NM_001365633.1; NM_001365634.1; NM_001375694.1; NM_001375697.1; NM_001375700.1; NM_001375701.1; NM_001375703.1; NM_001375705.1; NM_001375713.1; NM_001375715.1; NM_001375716.1; NM_001375718.1; NM_001375720.1; NM_015097.3; XM_006713040.1; XM_006713041.1; XM_006713042.1; XM_006713048.1; XM_006713050.1; XM_006713052.1; XM_006713053.1; XM_011533515.1; XM_017005947.1; XM_017005948.1; XM_017005949.1; XM_017005950.1; XM_017005951.1; XM_017005954.1; XM_017005955.1; XM_017005956.1; XM_017005957.1; XM_017005959.1; XM_017005960.1; XM_017005963.1; XM_017005965.1; XM_017005968.2; XM_017005969.2; XM_017005970.2; XM_017005971.2; XM_017005972.2; XM_017005973.2; XM_017005976.2; XM_017005978.2; XM_017005979.2; XM_017005983.2; XM_017005984.2; XM_017005986.2; XM_024453408.1; XM_024453409.1; XM_024453410.1

Protein Identifiers

RefSeq (protein)
NP_001193973.1; NP_001352556.1; NP_001352557.1; NP_001352558.1; NP_001352559.1; NP_001352560.1; NP_001352561.1; NP_001352562.1; NP_001352563.1; NP_001362623.1; NP_001362626.1; NP_001362629.1; NP_001362630.1; NP_001362632.1; NP_001362634.1; NP_001362642.1; NP_001362644.1; NP_001362645.1; NP_001362647.1; NP_001362649.1; NP_055912.2; XP_006713103.1; XP_006713104.1; XP_006713105.1; XP_006713111.1; XP_006713113.1; XP_006713115.1; XP_006713116.1; XP_011531817.1; XP_016861436.1; XP_016861437.1; XP_016861438.1; XP_016861439.1; XP_016861440.1; XP_016861443.1; XP_016861444.1; XP_016861445.1; XP_016861446.1; XP_016861448.1; XP_016861449.1; XP_016861452.1; XP_016861454.1; XP_016861457.1; XP_016861458.1; XP_016861459.1; XP_016861460.1; XP_016861461.1; XP_016861462.1; XP_016861465.1; XP_016861467.1; XP_016861468.1; XP_016861472.1; XP_016861473.1; XP_016861475.1; XP_024309176.1; XP_024309177.1; XP_024309178.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
605853
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 92/7921 TCGA samples
  • Damaged in 34/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 72 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 2 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 560 cell lines

Gene Function

  • Not present in KEGG
  • 3/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials