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Results for CTU2


Expand for information on CTU2

CTU2

Description
cytosolic thiouridylase subunit 2
Aliases
C16orf84, MFRG, NCS2, UPF0432

Gene Identifiers

Entrez ID
348180
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
617057
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 29/7921 TCGA samples
  • Damaged in 1/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 56 protein(s)
  • Part of at least one complex

miRNA Interactions

  • No miRNA interactions

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 333/982 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials