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DENND2B
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DENND2B
Description
DENN domain containing 2B
Aliases
HTS1, ST5, p126
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001376495.1; NM_001376496.1; NM_001376497.1; NM_001376498.1; NM_001376499.1; NM_001376500.1; NM_001376501.1; NM_001376502.1; NM_001376503.1; NM_001376504.1; NM_001376505.1; NM_001376506.1; NM_005418.4; NM_139157.3; NM_213618.2; XM_005253077.1; XM_011520309.1; XM_011520320.1; XM_011520321.2; XM_011520322.1; XM_011520324.2; XM_011520329.1
Protein Identifiers
RefSeq (protein)
NP_001363424.1; NP_001363425.1; NP_001363426.1; NP_001363427.1; NP_001363428.1; NP_001363429.1; NP_001363430.1; NP_001363431.1; NP_001363432.1; NP_001363433.1; NP_001363434.1; NP_001363435.1; NP_005409.3; NP_631896.1; NP_998783.1; XP_005253134.1; XP_011518611.1; XP_011518622.1; XP_011518623.1; XP_011518624.1; XP_011518626.2; XP_011518631.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 43/7921 TCGA samples
- Damaged in 18/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants