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DEPDC5
Expand for information on DEPDC5
DEPDC5
Description
DEP domain containing 5, GATOR1 subcomplex subunit
Aliases
DEP.5, FFEVF, FFEVF1
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001007188.3; NM_001136029.3; NM_001242896.3; NM_001242897.2; NM_001363852.2; NM_001363854.2; NM_001364318.1; NM_001364319.1; NM_001364320.1; NM_001369901.1; NM_001369902.1; NM_001369903.1; NM_014662.5; XM_011530557.2; XM_011530561.2; XM_011530562.2; XM_011530563.2; XM_011530565.2; XM_011530568.2; XM_011530569.2; XM_017029113.1; XM_017029114.1; XM_017029115.1; XM_024452305.1
Protein Identifiers
RefSeq (protein)
NP_001007189.1; NP_001129501.1; NP_001229825.1; NP_001229826.1; NP_001350781.1; NP_001350783.1; NP_001351247.1; NP_001351248.1; NP_001351249.1; NP_001356830.1; NP_001356831.1; NP_001356832.1; NP_055477.1; XP_011528859.1; XP_011528863.1; XP_011528864.1; XP_011528865.1; XP_011528867.1; XP_011528870.1; XP_011528871.1; XP_016884602.1; XP_016884603.1; XP_016884604.1; XP_024308073.1
Uniprot ID
Ensembl protein ID
ENSP00000383101.3; ENSP00000493489.1; ENSP00000498382.1; ENSP00000440210.1; ENSP00000494406.1; ENSP00000495544.1; ENSP00000371546.4; ENSP00000496724.1; ENSP00000383108.3; ENSP00000494879.1; ENSP00000410544.2; ENSP00000495917.1; ENSP00000383107.1; -; ENSP00000496395.1; ENSP00000494484.1; ENSP00000496281.1
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 135/7921 TCGA samples
- Damaged in 40/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants