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Results for ESRRG


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ESRRG

Description
estrogen related receptor gamma
Aliases
ERR-gamma, ERR3, ERRg, ERRgamma, NR3B3

Gene Identifiers

Entrez ID
2104
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001134285.3; NM_001243505.2; NM_001243506.2; NM_001243507.2; NM_001243509.2; NM_001243510.3; NM_001243511.3; NM_001243512.1; NM_001243513.1; NM_001243514.2; NM_001243515.2; NM_001243518.2; NM_001243519.1; NM_001350122.2; NM_001350123.2; NM_001350124.2; NM_001350125.2; NM_001438.4; NM_206594.2; NM_206595.3; XM_011509265.3; XM_011509266.3; XM_011509267.1; XM_011509268.2; XM_011509269.2; XM_011509271.2; XM_011509274.1; XM_011509275.1; XM_011509276.1; XM_011509277.1; XM_011509278.1; XM_011509279.1; XM_011509280.2; XM_017000621.2; XM_017000622.1; XM_017000623.2; XM_017000624.2; XM_017000625.1; XM_017000626.1; XM_017000627.1; XM_017000628.1; XM_017000630.1; XM_017000631.2; XM_017000632.2; XM_017000633.1; XM_017000634.2; XM_017000635.1; XM_017000636.2; XM_017000637.1; XM_017000638.2; XM_017000639.1; XM_017000641.1; XM_017000644.1; XM_017000645.1; XM_024453959.1; XM_024453960.1; XM_024453975.1; XM_024453979.1; XM_024453980.1

Protein Identifiers

RefSeq (protein)
NP_001127757.1; NP_001230434.1; NP_001230435.1; NP_001230436.1; NP_001230438.1; NP_001230439.1; NP_001230440.1; NP_001230441.1; NP_001230442.1; NP_001230443.1; NP_001230444.1; NP_001230447.1; NP_001230448.1; NP_001337051.1; NP_001337052.1; NP_001337053.1; NP_001337054.1; NP_001429.2; NP_996317.1; NP_996318.1; XP_011507567.1; XP_011507568.1; XP_011507569.1; XP_011507570.1; XP_011507571.1; XP_011507573.1; XP_011507576.1; XP_011507577.1; XP_011507578.1; XP_011507579.1; XP_011507580.1; XP_011507581.1; XP_011507582.1; XP_016856110.1; XP_016856111.1; XP_016856112.1; XP_016856113.1; XP_016856114.1; XP_016856115.1; XP_016856116.1; XP_016856117.1; XP_016856119.1; XP_016856120.1; XP_016856121.1; XP_016856122.1; XP_016856123.1; XP_016856124.1; XP_016856125.1; XP_016856126.1; XP_016856127.1; XP_016856128.1; XP_016856130.1; XP_016856133.1; XP_016856134.1; XP_024309727.1; XP_024309728.1; XP_024309743.1; XP_024309747.1; XP_024309748.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
602969
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 315/7921 TCGA samples
  • Damaged in 20/1291 cell lines

Evolutionary Conservation

  • Metazoans

Gene Duplication

  • One duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 67 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 12 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 1/1121 cell lines

Gene Function

  • Not present in KEGG
  • 1/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials