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G2E3
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G2E3
Description
G2/M-phase specific E3 ubiquitin protein ligase
Aliases
KIAA1333, PHF7B
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
Protein Identifiers
RefSeq (protein)
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 114/7921 TCGA samples
- Damaged in 24/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants