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Results for GNAI2


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GNAI2

Description
G protein subunit alpha i2
Aliases
GIPB, H_LUCA15.1, H_LUCA16.1, GNAI2

Gene Identifiers

Entrez ID
Ensembl Gene ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Candidate cancer driver, TIME driver
  • Damaged in 19/7921 TCGA samples
  • Damaged in 11/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • 2 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 169 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 47 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 8/1122 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials