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Results for H2AC17


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H2AC17

Description
H2A clustered histone 17
Aliases
H2A.1, H2A/n, H2AC11, H2AC13, H2AC15, H2AC16, H2AFN, HIST1H2AM, dJ193B12.1

Gene Identifiers

Entrez ID
8336
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
602796
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 97/7921 TCGA samples
  • Damaged in 2/1291 cell lines

Evolutionary Conservation

  • Eukaryotes

Gene Duplication

  • 19 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 228 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 4 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 319/1061 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials