Home Query results

Results for H2AC20


Expand for information on H2AC20

H2AC20

Description
H2A clustered histone 20
Aliases
H2A, H2A-GL101, H2A/q, H2AFQ, HIST2H2AC

Gene Identifiers

Entrez ID
8338
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
602797
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 378/7921 TCGA samples
  • Damaged in 22/1291 cell lines

Evolutionary Conservation

  • Eukaryotes

Gene Duplication

  • 20 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 238 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 25 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 234/1027 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials