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Results for H2AC7


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H2AC7

Description
H2A clustered histone 7
Aliases
H2A.3, H2A/g, H2AFG, HIST1H2AD

Gene Identifiers

Entrez ID
3013
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
602792
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 109/7921 TCGA samples
  • Damaged in 10/1291 cell lines

Evolutionary Conservation

  • Eukaryotes

Gene Duplication

  • 19 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 35 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 21 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 16/1061 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials