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HECW1
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HECW1
Description
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Aliases
NEDL1
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001287059.2; NM_015052.5; XM_005249665.4; XM_006715670.3; XM_006715671.3; XM_006715673.3; XM_011515220.3; XM_011515222.2; XM_011515223.2; XM_011515224.2; XM_011515225.2; XM_011515226.3; XM_017011882.1; XM_017011883.2; XM_017011884.1; XM_017011885.1; XM_017011886.1; XM_017011887.1; XM_017011888.1; XM_017011889.1; XM_017011890.1
Protein Identifiers
RefSeq (protein)
NP_001273988.1; NP_055867.3; XP_005249722.1; XP_006715733.1; XP_006715734.1; XP_006715736.1; XP_011513522.1; XP_011513524.1; XP_011513525.1; XP_011513526.1; XP_011513527.2; XP_011513528.1; XP_016867371.1; XP_016867372.1; XP_016867373.1; XP_016867374.1; XP_016867375.1; XP_016867376.1; XP_016867377.1; XP_016867378.1; XP_016867379.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 321/7921 TCGA samples
- Damaged in 49/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants