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HUWE1
Expand for information on HUWE1
HUWE1
Description
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Aliases
ARF-BP1, HECTH9, HSPC272, Ib772, LASU1, MRXST, MULE, URE-B1, UREB1
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_031407.7; XM_005261965.4; XM_011530747.1; XM_011530751.2; XM_017029191.1; XM_017029192.1; XM_017029193.1; XM_017029194.1; XM_017029195.1; XM_017029196.1; XM_017029197.1; XM_017029198.2; XM_017029199.1; XM_017029200.1; XM_017029201.1; XM_017029202.1; XM_017029203.1; XM_017029204.1; XM_017029206.1; XM_024452322.1
Protein Identifiers
RefSeq (protein)
NP_113584.3; XP_005262022.1; XP_011529049.1; XP_011529053.1; XP_016884680.1; XP_016884681.1; XP_016884682.1; XP_016884683.1; XP_016884684.1; XP_016884685.1; XP_016884686.1; XP_016884687.1; XP_016884688.1; XP_016884689.1; XP_016884690.1; XP_016884691.1; XP_016884692.1; XP_016884693.1; XP_016884695.1; XP_024308090.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver, TIME driver
- Damaged in 595/7921 TCGA samples
- Damaged in 57/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants