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Results for KHSRP


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KHSRP

Description
KH-type splicing regulatory protein
Aliases
FBP2, FUBP2, KSRP, p75

Gene Identifiers

Entrez ID
Ensembl Gene ID

mRNA Identifiers

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Candidate cancer driver
  • Damaged in 49/7921 TCGA samples
  • Damaged in 19/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • One duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 136 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 176 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 20/1122 cell lines

Gene Function

  • Not present in KEGG
  • 2/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials