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Results for KIR3DL1


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KIR3DL1

Description
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
Aliases
CD158E1, KIR/S1, NKAT-3, NKAT3, NKB1, NKB1B, KIR3DL1

Gene Identifiers

Entrez ID
3811
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
604946
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 12/7921 TCGA samples
  • Damaged in 13/1291 cell lines

Evolutionary Conservation

  • Mammals

Gene Duplication

  • 4 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 12 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with one miRNA

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1064 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials