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Results for LRRC37A3


Expand for information on LRRC37A3

LRRC37A3

Description
leucine rich repeat containing 37 member A3
Aliases
LRRC37, LRRC37A

Gene Identifiers

Entrez ID
374819
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
616557
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 134/7921 TCGA samples
  • Damaged in 4/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • 4 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 1 protein(s)
  • Part of zero complexes

miRNA Interactions

  • No miRNA interactions

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 52/980 cell lines

Gene Function

  • Not present in KEGG
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials