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Results for MAP7

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MAP7

Description

microtubule associated protein 7

Aliases

E-MAP-115, EMAP115

Gene Identifiers

Entrez ID

9053

Ensembl Gene ID

ENSG00000135525

mRNA Identifiers

RefSeq (mRNA)

NM_001198608.1; NM_001198609.1; NM_001198611.1; NM_001198614.1; NM_001198615.1; NM_001198616.1; NM_001198617.1; NM_001198618.1; NM_001198619.1; NM_003980.4; XM_006715598.3; XM_006715599.3; XM_006715600.3; XM_006715601.4; XM_011536243.2; XM_011536244.3; XM_011536245.2; XM_011536246.2; XM_017011471.2

Protein Identifiers

RefSeq (protein)

NP_001185537.1; NP_001185538.1; NP_001185540.1; NP_001185543.1; NP_001185544.1; NP_001185545.1; NP_001185546.1; NP_001185547.1; NP_001185548.1; NP_003971.1; XP_006715661.1; XP_006715662.1; XP_006715663.1; XP_006715664.1; XP_011534545.1; XP_011534546.1; XP_011534547.1; XP_011534548.1; XP_016866960.1

Uniprot ID

Q14244; Q14244; A0A087WZ40; B7Z3E1; Q14244; Q14244; B7ZB64; Q14244; Q14244; Q14244; Q14244; B7Z3Y3; Q14244; Q14244; A0A087WZ40; A0A087WZ40; Q14244; Q14244

Ensembl protein ID

ENSP00000482335.1; ENSP00000400790.2; ENSP00000414712.1; ENSP00000445737.1; ENSP00000482356.1; ENSP00000483511.1; ENSP00000414879.2; ENSP00000482998.1; ENSP00000346581.2

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

604108

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Candidate cancer driver
Damaged in 92/7921 TCGA samples
Damaged in 17/1291 cell lines

Evolutionary Conservation

Metazoans

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

26/30 tissues in GTEx
39/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

632/1019 in CCLE
952/970 in CLP
432/675 in GenenTech

Protein Expression in Tissues

40/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 173 protein(s)
Part of zero complexes

miRNA Interactions

Interacts with 56 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Equal damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Not essential in 982 cell lines

Gene Function

Not present in KEGG
Not present in Reactome

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers