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Results for MYD88


Expand for information on MYD88

MYD88

Description
MYD88 innate immune signal transduction adaptor
Aliases
IMD68D, MYD88

Gene Identifiers

Entrez ID
4615
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
602170
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Oncogene
  • Damaged in 28/7921 TCGA samples
  • Damaged in 12/1291 cell lines

Evolutionary Conservation

  • Metazoans

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 72 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 9 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1120 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials