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Results for MYO9A

Expand for information on MYO9A

MYO9A

Description

myosin IXA

Aliases

CMS24

Gene Identifiers

Entrez ID

4649

Ensembl Gene ID

ENSG00000066933

mRNA Identifiers

RefSeq (mRNA)

NM_006901.4; XM_006720539.3; XM_011521613.3; XM_011521614.3; XM_011521615.3; XM_011521616.3; XM_011521617.3; XM_011521618.3; XM_011521619.3; XM_011521620.3; XM_011521621.3; XM_011521622.3; XM_011521623.3; XM_017022229.1; XM_017022230.2

Protein Identifiers

RefSeq (protein)

NP_008832.2; XP_006720602.1; XP_011519915.1; XP_011519916.1; XP_011519917.1; XP_011519918.1; XP_011519919.1; XP_011519920.1; XP_011519921.1; XP_011519922.1; XP_011519923.1; XP_011519924.1; XP_011519925.1; XP_016877718.1; XP_016877719.1

Uniprot ID

B2RTY4; B2RTY4

Ensembl protein ID

ENSP00000348349.5; ENSP00000457945.1

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

604875

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Candidate cancer driver
Damaged in 121/7921 TCGA samples
Damaged in 34/1291 cell lines

Evolutionary Conservation

Last Universal Common Ancestor

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

28/30 tissues in GTEx
42/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

987/1019 in CCLE
945/970 in CLP
661/675 in GenenTech

Protein Expression in Tissues

45/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 59 protein(s)
Part of zero complexes

miRNA Interactions

Interacts with 7 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Equal damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Not essential in 1095 cell lines

Gene Function

Not present in KEGG
1/26 level 1 Reactome pathways

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers