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Results for OBI1


Expand for information on OBI1

OBI1

Description
ORC ubiquitin ligase 1
Aliases
C13orf7, RNF219

Gene Identifiers

Entrez ID
79596
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
615906
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 148/7921 TCGA samples
  • Damaged in 15/1291 cell lines

Evolutionary Conservation

  • Metazoans

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 83 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 23 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1021 cell lines

Gene Function

  • Not present in KEGG
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials