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Results for OPALIN


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OPALIN

Description
oligodendrocytic myelin paranodal and inner loop protein
Aliases
HTMP10, TMEM10, TMP10

Gene Identifiers

Entrez ID
Ensembl Gene ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Candidate cancer driver
  • Damaged in 4/7921 TCGA samples
  • Damaged in 0/1291 cell lines

Evolutionary Conservation

  • Mammals

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 207 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 2 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1015 cell lines

Gene Function

  • Not present in KEGG
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials