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PAK3
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PAK3
Description
p21 (RAC1) activated kinase 3
Aliases
ARA, MRX30, MRX47, OPHN3, PAK-3beta, bPAK, beta-PAK, PAK3
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001128166.2; NM_001128167.2; NM_001128168.3; NM_001128172.2; NM_001128173.3; NM_001324325.2; NM_001324326.2; NM_001324327.2; NM_001324328.2; NM_001324329.2; NM_001324330.2; NM_001324331.2; NM_001324332.2; NM_001324333.2; NM_001324334.2; NM_002578.5; XM_005262132.2; XM_005262133.3; XM_006724654.2; XM_006724655.2; XM_011530962.1; XM_011530967.2; XM_011530968.2; XM_011530969.1; XM_011530971.2; XM_017029557.1; XM_017029558.1; XM_017029559.1; XM_017029560.1; XM_017029561.2; XM_017029562.1; XM_017029563.1
Protein Identifiers
RefSeq (protein)
NP_001121638.1; NP_001121639.1; NP_001121640.1; NP_001121644.1; NP_001121645.1; NP_001311254.1; NP_001311255.1; NP_001311256.1; NP_001311257.1; NP_001311258.1; NP_001311259.1; NP_001311260.1; NP_001311261.1; NP_001311262.1; NP_001311263.1; NP_002569.1; XP_005262189.1; XP_005262190.1; XP_006724717.1; XP_006724718.1; XP_011529264.1; XP_011529269.1; XP_011529270.1; XP_011529271.1; XP_011529273.1; XP_016885046.1; XP_016885047.1; XP_016885048.1; XP_016885049.1; XP_016885050.1; XP_016885051.1; XP_016885052.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 60/7921 TCGA samples
- Damaged in 16/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants