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Results for PPP6R2


Expand for information on PPP6R2

PPP6R2

Description
protein phosphatase 6 regulatory subunit 2
Aliases
KIAA0685, PP6R2, SAP190, SAPS2

Gene Identifiers

Entrez ID
9701
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001242898.2; NM_001242899.2; NM_001242900.2; NM_001351641.2; NM_001351642.2; NM_001351643.2; NM_001351644.2; NM_001351645.2; NM_001351646.2; NM_001351647.2; NM_001351648.2; NM_001365836.1; NM_014678.5; XM_006724431.3; XM_011530720.2; XM_011530721.2; XM_011530722.2; XM_011530723.2; XM_011530724.2; XM_011530726.2; XM_011530727.2; XM_011530728.2; XM_011530729.2; XM_011530730.2; XM_011530731.1; XM_011530732.2; XM_011530734.2; XM_011530735.2; XM_011530736.3; XM_011530737.2; XM_011530738.2; XM_011530739.2; XM_011530740.2; XM_017029116.1; XM_017029117.1; XM_017029118.1; XM_017029119.1; XM_017029120.1; XM_017029121.1; XM_017029122.2; XM_017029123.1; XM_017029124.2; XM_017029127.2; XM_017029129.1; XM_017029130.1; XM_017029132.1; XM_017029133.1; XM_017029134.1; XM_017029135.1; XM_017029136.1; XM_024452306.1; XM_024452307.1

Protein Identifiers

RefSeq (protein)
NP_001229827.1; NP_001229828.1; NP_001229829.1; NP_001338570.1; NP_001338571.1; NP_001338572.1; NP_001338573.1; NP_001338574.1; NP_001338575.1; NP_001338576.1; NP_001338577.1; NP_001352765.1; NP_055493.2; XP_006724494.1; XP_011529022.1; XP_011529023.1; XP_011529024.1; XP_011529025.1; XP_011529026.1; XP_011529028.1; XP_011529029.1; XP_011529030.1; XP_011529031.1; XP_011529032.1; XP_011529033.1; XP_011529034.1; XP_011529036.1; XP_011529037.1; XP_011529038.1; XP_011529039.1; XP_011529040.1; XP_011529041.1; XP_011529042.1; XP_016884605.1; XP_016884606.1; XP_016884607.1; XP_016884608.1; XP_016884609.1; XP_016884610.1; XP_016884611.1; XP_016884612.1; XP_016884613.1; XP_016884616.1; XP_016884618.1; XP_016884619.1; XP_016884621.1; XP_016884622.1; XP_016884623.1; XP_016884624.1; XP_016884625.1; XP_024308074.1; XP_024308075.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
610877
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 52/7921 TCGA samples
  • Damaged in 16/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 87 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 5 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1021 cell lines

Gene Function

  • Not present in KEGG
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials