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Results for PRAMEF4


Expand for information on PRAMEF4

PRAMEF4

Description
PRAME family member 4
Aliases

Gene Identifiers

Entrez ID
400735
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 12/7921 TCGA samples
  • Damaged in 36/1291 cell lines

Evolutionary Conservation

  • Mammals

Gene Duplication

  • 10 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

  • Not expressed in any cancer cell line

Protein Expression in Tissues

Protein Interactions

  • Interacts with 2 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 14 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 967 cell lines

Gene Function

  • Not present in KEGG
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials