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PRUNE2
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PRUNE2
Description
prune homolog 2 with BCH domain
Aliases
BMCC1, BNIPXL, C9orf65, KIAA0367
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001308047.1; NM_001308048.1; NM_001308049.1; NM_001308050.1; NM_001308051.1; NM_001330680.1; NM_015225.3; XM_005251745.1; XM_005251746.1; XM_005251748.1; XM_005251750.1; XM_005251751.1; XM_005251754.2; XM_006716982.1; XM_006716983.1; XM_006716984.2; XM_006716985.1; XM_006716986.1; XM_011518323.2; XM_011518326.2; XM_011518327.1; XM_011518328.2; XM_017014345.2; XM_017014346.1; XM_017014347.2; XM_017014348.1; XM_017014349.1; XM_017014350.1; XM_017014351.1; XM_017014352.1; XM_017014353.2; XM_017014354.2; XM_017014356.2; XM_017014357.2; XM_017014358.2; XM_017014359.2
Protein Identifiers
RefSeq (protein)
NP_001294976.1; NP_001294977.1; NP_001294978.1; NP_001294979.1; NP_001294980.1; NP_001317609.1; NP_056040.2; XP_005251802.1; XP_005251803.1; XP_005251805.1; XP_005251807.1; XP_005251808.1; XP_005251811.1; XP_006717045.1; XP_006717046.1; XP_006717047.1; XP_006717048.1; XP_006717049.1; XP_011516625.1; XP_011516628.1; XP_011516629.1; XP_011516630.1; XP_016869834.1; XP_016869835.1; XP_016869836.1; XP_016869837.1; XP_016869838.1; XP_016869839.1; XP_016869840.1; XP_016869841.1; XP_016869842.1; XP_016869843.1; XP_016869845.1; XP_016869846.1; XP_016869847.1; XP_016869848.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 100/7921 TCGA samples
- Damaged in 26/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants