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RAPGEF1
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RAPGEF1
Description
Rap guanine nucleotide exchange factor 1
Aliases
C3G, GRF2
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001304275.2; NM_001377935.1; NM_001377936.1; NM_001377937.1; NM_001377938.1; NM_005312.4; NM_198679.2; XM_005272186.4; XM_006717067.3; XM_006717072.3; XM_006717074.3; XM_011518569.3; XM_011518570.3; XM_011518571.2; XM_011518572.2; XM_011518573.3; XM_011518574.3; XM_011518575.3; XM_011518576.3; XM_011518577.3; XM_011518578.3; XM_011518579.3; XM_011518580.3; XM_011518581.3; XM_011518582.3; XM_017014633.1; XM_017014634.1; XM_017014635.2; XM_017014636.2; XM_017014637.2; XM_017014638.2; XM_017014639.2; XM_017014640.2; XM_017014641.2; XM_024447521.1
Protein Identifiers
RefSeq (protein)
NP_001291204.1; NP_001364864.1; NP_001364865.1; NP_001364866.1; NP_001364867.1; NP_005303.2; NP_941372.1; XP_005272243.1; XP_006717130.1; XP_006717135.1; XP_006717137.1; XP_011516871.1; XP_011516872.1; XP_011516873.1; XP_011516874.1; XP_011516875.1; XP_011516876.1; XP_011516877.1; XP_011516878.1; XP_011516879.1; XP_011516880.1; XP_011516881.1; XP_011516882.1; XP_011516883.1; XP_011516884.1; XP_016870122.1; XP_016870123.1; XP_016870124.1; XP_016870125.1; XP_016870126.1; XP_016870127.1; XP_016870128.1; XP_016870129.1; XP_016870130.1; XP_024303289.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 62/7921 TCGA samples
- Damaged in 16/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants