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Results for RBFOX1


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RBFOX1

Description
RNA binding fox-1 homolog 1
Aliases
2BP1, A2BP1, FOX-1, FOX1, HRNBP1

Gene Identifiers

Entrez ID
54715
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001142333.2; NM_001142334.1; NM_001308117.1; NM_001364800.2; NM_018723.4; NM_145891.3; NM_145892.3; NM_145893.3; XM_005255386.4; XM_005255387.4; XM_005255390.4; XM_005255391.4; XM_005255394.4; XM_011522546.2; XM_011522547.2; XM_011522548.2; XM_017023318.2; XM_017023319.2; XM_017023320.2; XM_017023321.2; XM_017023322.2; XM_017023323.2; XM_017023324.2; XM_017023326.2; XM_017023327.1; XM_017023328.2; XM_017023329.2; XM_017023330.1; XM_017023331.2; XM_017023332.1; XM_017023333.1; XM_017023334.1; XM_017023336.1; XM_017023337.1; XM_017023338.1; XM_017023340.1; XM_017023341.2; XM_017023342.1; XM_024450303.1; XM_024450304.1; XM_024450305.1; XM_024450306.1; XM_024450307.1; XM_024450308.1; XM_024450309.1; XM_024450310.1; XM_024450311.1; XM_024450312.1; XM_024450313.1; XM_024450314.1; XM_024450315.1; XM_024450316.1

Protein Identifiers

RefSeq (protein)
NP_001135805.1; NP_001135806.1; NP_001295046.1; NP_001351729.1; NP_061193.2; NP_665898.1; NP_665899.1; NP_665900.1; XP_005255443.1; XP_005255444.1; XP_005255447.1; XP_005255448.1; XP_005255451.1; XP_011520848.1; XP_011520849.1; XP_011520850.1; XP_016878807.1; XP_016878808.1; XP_016878809.1; XP_016878810.1; XP_016878811.1; XP_016878812.1; XP_016878813.1; XP_016878815.1; XP_016878816.1; XP_016878817.1; XP_016878818.1; XP_016878819.1; XP_016878820.1; XP_016878821.1; XP_016878822.1; XP_016878823.1; XP_016878825.1; XP_016878826.1; XP_016878827.1; XP_016878829.1; XP_016878830.1; XP_016878831.1; XP_024306071.1; XP_024306072.1; XP_024306073.1; XP_024306074.1; XP_024306075.1; XP_024306076.1; XP_024306077.1; XP_024306078.1; XP_024306079.1; XP_024306080.1; XP_024306081.1; XP_024306082.1; XP_024306083.1; XP_024306084.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
605104
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 50/7921 TCGA samples
  • Damaged in 22/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 71 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 15 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 1/1122 cell lines

Gene Function

  • Not present in KEGG
  • 1/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials