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Results for RIMS1


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RIMS1

Description
regulating synaptic membrane exocytosis 1
Aliases
CORD7, RAB3IP2, RIM, RIM1

Gene Identifiers

Entrez ID
22999
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001168407.2; NM_001168408.2; NM_001168409.2; NM_001168410.2; NM_001168411.2; NM_001350411.1; NM_001350412.1; NM_001350413.1; NM_001350414.2; NM_001350415.2; NM_001350416.2; NM_001350417.2; NM_001350418.2; NM_001350419.2; NM_001350420.2; NM_001350421.2; NM_001350422.2; NM_001350423.2; NM_001350424.2; NM_001350425.2; NM_001350426.2; NM_001350427.2; NM_001350428.2; NM_001350429.2; NM_001350430.2; NM_001350431.2; NM_001350432.2; NM_001350433.2; NM_001350434.2; NM_001350435.2; NM_001350436.2; NM_001350437.2; NM_001350438.2; NM_001350439.2; NM_001350440.2; NM_001350441.2; NM_001350442.2; NM_001350443.2; NM_001350444.2; NM_001350445.2; NM_001350446.2; NM_001350447.2; NM_001350448.2; NM_001350449.2; NM_001350450.2; NM_001350452.2; NM_001350454.2; NM_001350455.2; NM_001350456.2; NM_001350457.2; NM_001350458.2; NM_001350459.2; NM_001350460.2; NM_001350461.2; NM_001350462.2; NM_001350463.2; NM_001350464.2; NM_001350465.2; NM_001350466.2; NM_001350467.2; NM_001350468.2; NM_001350469.2; NM_001350470.2; NM_001350471.2; NM_001350472.2; NM_001350473.2; NM_001350474.2; NM_014989.5; XM_005248688.4; XM_011535604.3; XM_017010516.2; XM_017010517.2; XM_017010518.2; XM_017010519.2; XM_017010520.2; XM_017010521.2; XM_017010522.2; XM_017010523.2; XM_017010524.2; XM_017010525.2; XM_017010526.2; XM_017010527.2; XM_017010537.2; XM_017010544.2; XM_017010546.2; XM_017010556.2; XM_017010557.2; XM_017010558.2; XM_024446369.1; XM_024446370.1; XM_024446371.1; XM_024446372.1

Protein Identifiers

RefSeq (protein)
NP_001161879.1; NP_001161880.1; NP_001161881.1; NP_001161882.1; NP_001161883.1; NP_001337340.1; NP_001337341.1; NP_001337342.1; NP_001337343.1; NP_001337344.1; NP_001337345.1; NP_001337346.1; NP_001337347.1; NP_001337348.1; NP_001337349.1; NP_001337350.1; NP_001337351.1; NP_001337352.1; NP_001337353.1; NP_001337354.1; NP_001337355.1; NP_001337356.1; NP_001337357.1; NP_001337358.1; NP_001337359.1; NP_001337360.1; NP_001337361.1; NP_001337362.1; NP_001337363.1; NP_001337364.1; NP_001337365.1; NP_001337366.1; NP_001337367.1; NP_001337368.1; NP_001337369.1; NP_001337370.1; NP_001337371.1; NP_001337372.1; NP_001337373.1; NP_001337374.1; NP_001337375.1; NP_001337376.1; NP_001337377.1; NP_001337378.1; NP_001337379.1; NP_001337381.1; NP_001337383.1; NP_001337384.1; NP_001337385.1; NP_001337386.1; NP_001337387.1; NP_001337388.1; NP_001337389.1; NP_001337390.1; NP_001337391.1; NP_001337392.1; NP_001337393.1; NP_001337394.1; NP_001337395.1; NP_001337396.1; NP_001337397.1; NP_001337398.1; NP_001337399.1; NP_001337400.1; NP_001337401.1; NP_001337402.1; NP_001337403.1; NP_055804.2; XP_005248745.1; XP_011533906.2; XP_016866005.1; XP_016866006.1; XP_016866007.1; XP_016866008.1; XP_016866009.1; XP_016866010.1; XP_016866011.1; XP_016866012.1; XP_016866013.1; XP_016866014.1; XP_016866015.1; XP_016866016.1; XP_016866026.1; XP_016866033.1; XP_016866035.1; XP_016866045.1; XP_016866046.1; XP_016866047.1; XP_024302137.1; XP_024302138.1; XP_024302139.1; XP_024302140.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
606629
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 277/7921 TCGA samples
  • Damaged in 38/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 27 protein(s)
  • Part of at least one complex

miRNA Interactions

  • No miRNA interactions

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1029 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials