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Results for RIPOR2

Expand for information on RIPOR2

RIPOR2

Description

RHO family interacting cell polarization regulator 2

Aliases

C6orf32, DFNB104, DIFF40, DIFF48, FAM65B, MYONAP, PL48

Gene Identifiers

Entrez ID

9750

Ensembl Gene ID

ENSG00000111913

mRNA Identifiers

RefSeq (mRNA)

NM_001286445.3; NM_001286446.2; NM_001286447.1; NM_001346031.2; NM_001346032.2; NM_014722.5; NM_015864.4; XM_006715275.2; XM_006715279.2; XM_006715281.3; XM_011515007.1; XM_011515008.2; XM_011515009.1; XM_011515012.1; XM_017011523.1; XM_017011524.1; XM_017011525.1; XM_017011526.1; XM_017011527.1

Protein Identifiers

RefSeq (protein)

NP_001273374.1; NP_001273375.1; NP_001273376.1; NP_001332960.1; NP_001332961.1; NP_055537.2; NP_056948.2; XP_006715338.1; XP_006715342.1; XP_006715344.1; XP_011513309.1; XP_011513310.1; XP_011513311.1; XP_011513314.1; XP_016867012.1; XP_016867013.1; XP_016867014.1; XP_016867015.1; XP_016867016.1

Uniprot ID

B7Z5J9; F5GX51; Q9Y4F9; B7Z6U4; B7Z6D6; B7Z6D6; F5H029; Q9Y4F9; Q9Y4F9; A0A024QZY9; B7Z5J9; Q9Y4F9; A0A024R028; F5GX51; F5H029; A0A024R028; Q9Y4F9; A0A024R028; Q9Y4F9

Ensembl protein ID

ENSP00000494268.1; ENSP00000441305.1; ENSP00000438425.1; ENSP00000441138.2; ENSP00000259698.4; ENSP00000367262.4; ENSP00000495879.1; ENSP00000494150.1; ENSP00000495914.1; ENSP00000495245.1

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

611410

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Candidate cancer driver
Damaged in 160/7921 TCGA samples
Damaged in 26/1291 cell lines

Evolutionary Conservation

No orthology information

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

28/30 tissues in GTEx
42/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

230/1019 in CCLE
No data in CLP
150/675 in GenenTech

Protein Expression in Tissues

No data in The Protein Atlas

Protein Interactions

Interacts with 11 protein(s)
Part of zero complexes

miRNA Interactions

Interacts with 20 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Equal damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Not essential in 930 cell lines

Gene Function

Not present in KEGG
Not present in Reactome

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers