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SMUG1
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SMUG1
Description
single-strand-selective monofunctional uracil-DNA glycosylase 1
Aliases
FDG, HMUDG, UNG3
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001243787.1; NM_001243788.1; NM_001243789.2; NM_001243790.2; NM_001243791.2; NM_001351237.2; NM_001351238.2; NM_001351239.2; NM_001351240.2; NM_001351241.2; NM_001351242.1; NM_001351243.1; NM_001351244.1; NM_001351245.1; NM_001351246.1; NM_001351247.1; NM_001351248.1; NM_001351249.1; NM_001351250.1; NM_001351251.1; NM_001351252.1; NM_001351253.1; NM_001351254.1; NM_001351255.1; NM_001351256.1; NM_001351257.1; NM_001351258.2; NM_001351259.1; NM_001351260.1; NM_001351261.2; NM_001351262.1; NM_014311.2; XM_006719319.3; XM_011538112.2; XM_011538116.2; XM_011538118.2; XM_011538119.2; XM_011538121.2; XM_017019119.2; XM_024448913.1
Protein Identifiers
RefSeq (protein)
NP_001230716.1; NP_001230717.1; NP_001230718.1; NP_001230719.1; NP_001230720.1; NP_001338166.1; NP_001338167.1; NP_001338168.1; NP_001338169.1; NP_001338170.1; NP_001338171.1; NP_001338172.1; NP_001338173.1; NP_001338174.1; NP_001338175.1; NP_001338176.1; NP_001338177.1; NP_001338178.1; NP_001338179.1; NP_001338180.1; NP_001338181.1; NP_001338182.1; NP_001338183.1; NP_001338184.1; NP_001338185.1; NP_001338186.1; NP_001338187.1; NP_001338188.1; NP_001338189.1; NP_001338190.1; NP_001338191.1; NP_055126.1; XP_006719382.1; XP_011536414.1; XP_011536418.1; XP_011536420.1; XP_011536421.1; XP_011536423.1; XP_016874608.1; XP_024304681.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 44/7921 TCGA samples
- Damaged in 7/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants