Home Query results

Results for SPTA1


Expand for information on SPTA1

SPTA1

Description
spectrin alpha, erythrocytic 1
Aliases
EL2, HPP, HS3, SPH3, SPTA

Gene Identifiers

Entrez ID
6708
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
182860
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 456/7921 TCGA samples
  • Damaged in 53/1291 cell lines

Evolutionary Conservation

  • Mammals

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 80 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 14 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1064 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials