Gene query results

Home Query results

Results for STRADA

Expand for information on STRADA

STRADA

Description

STE20 related adaptor alpha

Aliases

LYK5, NY-BR-96, PMSE, STRAD, STRAD alpha, Stlk

Gene Identifiers

Entrez ID

92335

Ensembl Gene ID

ENSG00000266173

mRNA Identifiers

RefSeq (mRNA)

NM_001003786.3; NM_001003787.4; NM_001003788.3; NM_001165969.2; NM_001165970.2; NM_001363786.1; NM_001363787.1; NM_001363788.1; NM_001363789.1; NM_001363790.1; NM_001363791.1; NM_153335.6; XM_005257799.3; XM_005257801.5; XM_005257803.5; XM_011525466.3; XM_011525467.3; XM_017025314.2

Protein Identifiers

RefSeq (protein)

NP_001003786.1; NP_001003787.1; NP_001003788.1; NP_001159441.1; NP_001159442.1; NP_001350715.1; NP_001350716.1; NP_001350717.1; NP_001350718.1; NP_001350719.1; NP_001350720.1; NP_699166.2; XP_005257856.1; XP_005257858.1; XP_005257860.1; XP_011523768.1; XP_011523769.1; XP_016880803.1

Uniprot ID

Q86YC8; Q7RTN6; Q7RTN6; Q7RTN6; Q7RTN6; Q7RTN6; Q7RTN6; Q7RTN6; A0A1W2PS04; J3QQS3; A0A1W2PQF1; J3QS66

Ensembl protein ID

ENSP00000492578.1; ENSP00000336655.6; ENSP00000365000.4; ENSP00000462922.1; ENSP00000398841.3; ENSP00000491580.1; ENSP00000491528.1; ENSP00000492238.1; ENSP00000491922.1; ENSP00000376677.4; ENSP00000491017.1; ENSP00000492877.1; ENSP00000463872.2; ENSP00000491928.1; ENSP00000464547.2

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

608626

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Candidate cancer driver
Damaged in 159/7921 TCGA samples
Damaged in 16/1291 cell lines

Evolutionary Conservation

Last Universal Common Ancestor

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

30/30 tissues in GTEx
43/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

1019/1019 in CCLE
No data in CLP
675/675 in GenenTech

Protein Expression in Tissues

44/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 12 protein(s)
Part of at least one complex

miRNA Interactions

No miRNA interactions

Germline Variation vs. Expected

Fewer loss of function mutations
Equal damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Essential in 5/1088 cell lines

Gene Function

1/6 level 1 KEGG pathways
1/26 level 1 Reactome pathways

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers