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Results for TAS2R46


Expand for information on TAS2R46

TAS2R46

Description
taste 2 receptor member 46
Aliases
T2R46, T2R54

Gene Identifiers

Entrez ID
259292
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
612774
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 253/7921 TCGA samples
  • Damaged in 18/1291 cell lines

Evolutionary Conservation

  • Vertebrates

Gene Duplication

  • 7 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

  • No expression information

Protein Expression in Tissues

Protein Interactions

  • Interacts with protein(s)
  • Part of zero complexes

miRNA Interactions

  • No miRNA interactions

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 3/1064 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials