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Results for THRAP3


Expand for information on THRAP3

THRAP3

Description
thyroid hormone receptor associated protein 3
Aliases
BCLAF2, TRAP150

Gene Identifiers

Entrez ID
9967
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
603809
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 103/7921 TCGA samples
  • Damaged in 13/1291 cell lines

Evolutionary Conservation

  • Vertebrates

Gene Duplication

  • One duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 224 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 45 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 7/1082 cell lines

Gene Function

  • Not present in KEGG
  • 2/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials