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TLE4
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TLE4
Description
TLE family member 4, transcriptional corepressor
Aliases
BCE-1, BCE1, E(spI), E(spl), ESG, ESG4, GRG4, Grg-4
Gene Identifiers
mRNA Identifiers
RefSeq (mRNA)
NM_001282748.1; NM_001282749.1; NM_001282753.1; NM_001282760.1; NM_001351541.1; NM_001351542.1; NM_001351543.2; NM_001351546.2; NM_001351547.2; NM_001351550.1; NM_001351552.1; NM_001351556.2; NM_001351558.1; NM_001351560.2; NM_001351562.1; NM_001351563.2; NM_001351564.1; NM_007005.6; XM_006717264.1; XM_006717268.1; XM_011518952.1; XM_011518953.2; XM_011518954.1; XM_011518955.1; XM_011518956.1; XM_011518957.1; XM_011518958.1; XM_011518959.1; XM_011518960.1; XM_011518961.1; XM_011518962.1; XM_011518963.1; XM_011518964.1; XM_011518965.1; XM_011518966.1; XM_011518967.1; XM_011518968.1; XM_011518969.1; XM_011518970.3; XM_011518972.3; XM_017015067.1; XM_017015068.1; XM_017015069.2; XM_017015070.1; XM_017015074.1; XM_017015075.1; XM_017015081.1; XM_017015083.1; XM_024447659.1
Protein Identifiers
RefSeq (protein)
NP_001269677.1; NP_001269678.1; NP_001269682.1; NP_001269689.1; NP_001338470.1; NP_001338471.1; NP_001338472.1; NP_001338475.1; NP_001338476.1; NP_001338479.1; NP_001338481.1; NP_001338485.1; NP_001338487.1; NP_001338489.1; NP_001338491.1; NP_001338492.1; NP_001338493.1; NP_008936.2; XP_006717327.1; XP_006717331.1; XP_011517254.1; XP_011517255.1; XP_011517256.1; XP_011517257.1; XP_011517258.1; XP_011517259.1; XP_011517260.1; XP_011517261.1; XP_011517262.1; XP_011517263.1; XP_011517264.1; XP_011517265.1; XP_011517266.1; XP_011517267.1; XP_011517268.1; XP_011517269.1; XP_011517270.1; XP_011517271.1; XP_011517272.1; XP_011517274.1; XP_016870556.1; XP_016870557.1; XP_016870558.1; XP_016870559.1; XP_016870563.1; XP_016870564.1; XP_016870570.1; XP_016870572.1; XP_024303427.1
Uniprot ID
Ensembl protein ID
Protein Architecture
SMART
Disease Mapping
Druggability
- Candidate cancer driver
- Damaged in 63/7921 TCGA samples
- Damaged in 28/1291 cell lines
- Fewer loss of function mutations
- Equal damaging SNVs/indels
- Fewer structural variants