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Results for TUBA1C


Expand for information on TUBA1C

TUBA1C

Description
tubulin alpha 1c
Aliases
TUBA6, bcm948

Gene Identifiers

Entrez ID
84790
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver
  • Damaged in 41/7921 TCGA samples
  • Damaged in 11/1291 cell lines

Evolutionary Conservation

  • Eukaryotes

Gene Duplication

  • 12 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 344 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 9 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 345/1054 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials