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Results for ZNF226

Expand for information on ZNF226

ZNF226

Description

zinc finger protein 226

Aliases

Gene Identifiers

Entrez ID

7769

Ensembl Gene ID

ENSG00000167380

mRNA Identifiers

RefSeq (mRNA)

NM_001032372.1; NM_001032373.1; NM_001032374.1; NM_001146220.2; NM_001319088.1; NM_001319089.1; NM_001319090.1; NM_015919.3; NM_016444.2; XM_005259227.2; XM_006723367.3; XM_006723368.3; XM_006723369.2; XM_017027262.1; XM_017027263.1; XM_017027264.1; XM_017027265.1

Protein Identifiers

RefSeq (protein)

NP_001027544.1; NP_001027545.1; NP_001027546.1; NP_001139692.1; NP_001306017.1; NP_001306018.1; NP_001306019.1; NP_057003.2; NP_057528.2; XP_005259284.1; XP_006723430.1; XP_006723431.1; XP_006723432.1; XP_016882751.1; XP_016882752.1; XP_016882753.1; XP_016882754.1

Uniprot ID

A0A024R0P4; Q9NYT6; Q9NYT6; A0A024R0P4; Q9NYT6; Q9NYT6; B2RBM0; Q9NYT6; A0A024R0P4; Q9NYT6; A0A024R0P4; A0A024R0P4; Q9NYT6; Q9NYT6; A0A024R0P4; Q9NYT6; Q9NYT6; A0A024R0P4; A0A024R0P4; Q9NYT6; A0A024R0P4; Q9NYT6; Q9NYT6; A0A024R0P4; Q9NYT6; A0A024R0P4; Q9NR94; Q9NR94; Q9NYT6

Ensembl protein ID

ENSP00000393265.1; ENSP00000336719.5; ENSP00000407474.1; ENSP00000467003.1; ENSP00000300823.5; ENSP00000465121.1

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Candidate cancer driver
Damaged in 110/7921 TCGA samples
Damaged in 24/1291 cell lines

Evolutionary Conservation

Last Universal Common Ancestor

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

30/30 tissues in GTEx
43/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

996/1019 in CCLE
945/970 in CLP
669/675 in GenenTech

Protein Expression in Tissues

42/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 6 protein(s)
Part of at least one complex

miRNA Interactions

Interacts with 39 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Equal damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Not essential in 1064 cell lines

Gene Function

1/6 level 1 KEGG pathways
1/26 level 1 Reactome pathways

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers